The specific rankings of online gambling operators may vary depending on various factors such as jurisdiction, market conditions, and time of measurement. However, here are ten major online gambling operators that have a considerable number of users based on their global reach and popularity:
1. Bet365
2. 888 Holdings
3. William Hill
4. PokerStars
5. Paddy Power Betfair
6. GVC Holdings
7. Kindred Group
8. DraftKings
9. Flutter Entertainment
10. Betway
Please note that this ranking is not definitive and can change over time.